Monaco starred alongside singer and fellow Dancing with the Stars contestant Mel B, a.k.a.Scary Spice, until June 2009, when Monaco's contract expired and she was replaced by Holly Madison.
In 2009, she traveled to Kenya with Feed the Children, as part of Daytime Gives Back.
She remains active with children’s charities and lives in Los Angeles.
On July 27, 2012 it was announced that Monaco will be participating in the 15th season of Dancing with the Stars for a chance to win a second mirrorball trophy.
This time she was partnered with Valentin Chmerkovskiy.
When that program ended, she joined the cast of ABC soap opera General Hospital as Samantha Mc Call in September 2003.
In 2003, Monaco was nominated for a Daytime Emmy Award for Outstanding Supporting Actress in a Drama Series for her role on Port Charles.Although she initially faced tough criticism from the judges, she maintained a positive outlook throughout the series.Among the events that she experienced prior to her victory were a near-wardrobe malfunction in which the skimpy strap on her dress during a Latin dance number came apart.On October 24, 2009, as part of the i Participate campaign, Monaco and several of her General Hospital co-stars volunteered to help beautify a school in Los Angeles. Monaco has 4 sisters; Christine, Marissa, Carmina and Amber.Monaco was in an 18-year relationship with her high school sweetheart, Michael Gonzalez, which began when she was 15 years old.In 2006, Monaco was again nominated for a Daytime Emmy, this time for Outstanding Lead Actress in a Drama Series for her role as Sam Mc Call on General Hospital.